FcεRI CHO
CBP74594
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| I. Background | |
| FcεRI是免疫球蛋白E（IgE）的高亲和力受体，由FCER1A基因编码，在肥大细胞和嗜碱性粒细胞表面表达。当IgE与FcεRI结合后，过敏原交联相邻受体复合物会激活下游信号通路，触发组胺等过敏介质释放，是I型超敏反应的核心启动分子。 | |
| II. Description | |
| FcεRI CHO细胞，在 CHO-K1细胞的基础上，稳定表达 FcεRI 。 | |
| III. Introduction | |
| Expressed gene: | FcεRI |
| Host Cell: | CHO |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: |
F12K+10%FBS+5 μg/ml Puromycin+5 μg/ml Blasticidin+1000 μg/ml G418
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| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Binding Assay,FACS |
| IV. Representative Data | |
 Figure 1. Recombinant FcεRI CHO constitutively expressing FcεRI. |
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